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expounded on the obesity paradox, suggesting increased BMD is offset by poor bone quality due to advanced glycation end-products (AGEs) accumulation, impaired osteoblast function, and uncoupled bone turnover favoring resorption
The current landing page's "fast weight loss" framing is more aggressive than the brand's earlier, more measured public materials
Other loci, such as glucokinase regulator (GCKR) and membrane bound O-acyltransferase domain-containing 7 (MBOAT7), influence glucose metabolism, phospholipid remodeling, and insulin sensitivity, highlighting the tight link between metabolic dysfunction and liver injury
For example, California, citing budget constraints, put Wegovy on a waiting list and limited it only to patients with certain co-conditions while studying overall impact
