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Given the high prevalence of CKD in MASLD patients and the shared pathophysiology, GLP-1-based therapies are particularly attractive in this comorbid population [15]

This may result from accelerated muscle growth, placing stress on joint structures

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[5] The work is early and mechanistic, but it points to a future where specific gut bacteria may be leveraged to support metabolic health, and it underscores how much of the GLP-1 story is written in the microbiome