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The stabilization and nuclear translocation of Nrf2 result in the transcription of antioxidant response element-regulated genes such as HO-1, NQO1, GCLC, SOD, catalase, and GPx, which together enhance glutathione synthesis, maintain mitochondrial redox balance, suppress lipid peroxidation, and improve cellular resilience to oxidative insults
Supplementary Table S2)
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2f), with a vast increase in metabolite abundance 72 h post treatment (Fig
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