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Clinical Profiles That May Justify the Stack The following profiles represent cases where the medical team at HealthRX has seen the most coherent rationale for co-administration: Post-surgical recovery in a patient receiving chronic corticosteroids or immunosuppressants

In most cases, GLP-1 medications are used to treat obesity and diabetes both of which are managed in primary care

PKF275-055, an analogue of vildagliptin and a DPP-4 inhibitor, counteracted changes in Na/K-ATPase activity, nerve conduction velocity, and nociceptive thresholds in diabetic rats [50]

74 Exenatide therapy was associated with lower cardiac enzyme values during the first 72 hours and a reduction in infarct size according to cardiac MRI at 1 month compared with placebo

These observations are consistent with clinical findings that side effects of GLP-1 receptor agonists often attenuate over time (Wharton et al