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The metastable state of disease-specific Syn variants (truncation and S129p) adds further strain to the already hydrophobic brain environment

However, in neurodegenerative diseases, the extent and functional relevance of such reactivation remain ambiguous

These effects were not reproduced in 3-AR knockout mice, suggesting that the 3-AR plays a key role in the compounds chronic metabolic effects (Heffernan et al

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Your mitochondrial function gets a boost, helping these cellular powerhouses produce energy more efficiently so you feel more vibrant