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Beltcheva M, Metcheva R, Popov N, et al

Semaglutide is an FDA-approved prescription medication with no psychoactive properties, and its use in the context of diabetes management or weight loss would not typically raise security concerns

Mechanistic human studies propose a GLP-1 kidney axis that helps control kidney function and fluid balance

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Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice

In some individuals, particularly early in treatment, these physiological effects may be accompanied by gastrointestinal symptoms such as nausea or early fullness