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and those not pregnant or planning a pregnancy

Methane, Motility, and GLP-1 Therapy Methane production is associated with slower intestinal transit and constipation-predominant physiology

Public health officials could take actions like prioritizing access to the people most likely to benefit from GLP-1s, encouraging the development of generic versions, and making them more easily available through primary care

AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool OpenAI GPT (version 5.5, released 2026-04-23) was used solely for language editing

This approval was significant because it marked the first time since 2014 that the FDA had approved a new drug for this purpose