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Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system [PMID: 35087020] Laboratory literature summary: Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38(+)

This result is suggestive of the constitutive activation of LKB1/AMPK pathway in the livers of KO mice

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This biochemical bottleneck is a crucial factor in understanding the deep, cellular exhaustion and post-exertional malaise experienced by patients with complex chronic illnesses