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Adding Tesofensine can provide the sympathetic drive needed to increase resting energy expenditure, while adding 5-Amino-1MQ can optimize cellular metabolism, effectively breaking the plateau without compromising patient comfort
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We included only comparative studies
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The relative abundance of the [ Eubacterium ] coprostanoligenes group was greater in both the vehicle- and 5A-1MQ-treated groups switched from WD to LD compared to the LD control group (Supplementary Fig
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