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SURMOUNT-1 reported approximately 20% to 22% body-weight reduction at the 15 mg dose over 72 weeks in a separate trial, compared with up to 10.8% with Cagrilintide monotherapy at week 26 [7]
The mid-range 10mg format supports controlled research applications and multiple experimental protocols
Neither agent individually holds MHRA marketing authorisation, and both remain in clinical development
The brain's appetite circuits also become desensitized over time if the same stimulus is applied continuously, meaning your body may eventually require higher doses or additional strategies to maintain the same suppression effect
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