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rosemary leaf extract
Mitochondrial dysfunction is a central feature of PD, with complex I of the electron transport chain being particularly affected
Similar findings of behavioral improvement without changes in infarct size have been seen by others, for example, a significant improvement in behavior was seen following treatment with a MEK/ERK inhibitor (U0126) 48 h after ischemia, yet the stroke volume remained unchanged [60]
Use one documented process across the study
Free Radical Biology and Medicine, 2004
Repeated dosing studies in rats, dogs, and mice for up to 6 weeks across doses from 0.006 mg/kg to 20 mg/kg via multiple routes showed excellent tolerance
