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The work of Lebrun et al now adds an important piece to this puzzle by describing a critical and previously unrecognized role for the gut-derived hormone glucagon-like-peptide 1 (GLP-1) in the regulation of intestinal inflammation

Wegovy prescriptions this year

* These statements have not been evaluated by the FDA

In a phase 2 trial, VK2735 showed nearly 15% weight loss after 13 weeks, with up to 88% of participants achieving a weight loss of at least 10%

These shortcomings diminish the reliability of the evidence and make it more difficult to reach strong conclusions about treatment efficacy

Papamargaritis D, le Roux CW, Sioka E, Koukoulis G, Tzovaras G, Zacharoulis D