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Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

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Because glutathione participates in so many important biological processes, maintaining healthy levels has become an important focus for individuals interested in supporting long-term wellness, healthy aging, and everyday vitality

specific cytokine profiling, dose-response relationships for anti-inflammatory endpoints, and comparison against established anti-inflammatory agents are all under-developed in the published record

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