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Oxidative stress can worsen MCAS, therefore anything that counters it is helpful in our approach to MCAS
In this study, vegan collagen (VC) was used and administered daily at 5 g versus fish collagen (FC) at 5 g for 8 weeks in 90 subjects divided into the placebo group ( n = 30), VC ( n = 30), and FC ( n = 30), and skin parameters were measured at baseline, week 4, and week 8, which included skin collagen density, elasticity, wrinkles, texture, hydration, and pore size
doi: 10.1038/s41586-019-1228-x 97 ZhangCShangGGuiXZhangXBaiX-CChenZJ
The subcutaneous injectable form is the most effective method because it bypasses the digestive system, ensuring 100% bioavailability and absorption
This is not well understood mechanistically but may relate to individual sensitivity, dehydration, or unrelated factors coinciding with supplement use
Nasal sprays avoid needles but deliver less predictable absorption, especially when nasal congestion is present
