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At the highest dose of 15 mg, participants lost an average of 48 lbs., while those on the lowest dose of 5 mg saw an average loss of 34 lbs., compared to just 7 lbs

You cant out-stubborn that

Most scales dont differentiate between weight/fat loss & muscle loss, for that reason, tracking only your weight isnt a reliable way to determine whether youre losing weight, fat, or muscle & in what amounts Conversely, a body fat scale can provide a more accurate picture of your body composition by measuring the percentage of all components Be sure to measure yourself on a weekly or bi-weekly schedule to understand the changes that are happening

The evidence is real but modest: trial data shows more fat loss than placebo over 12 weeks, not dramatic transformation

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Thus, they are quite promising for addressing sudden epidemic infectious diseases