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For an oral drug, the organ that receives the highest dose is the liver 50% of all drugs fail on liver toxicity Pfizer has not been so lucky
That is why nausea and flushing are common early complaints
doi: 10.3390/nu15173728 83 CummingsDEOverduinJ
Our literature review indicated that the effect of vasoconstriction is closely associated with elevated calcium concentration
The Bottom Line Esophageal irritation from stomach acid can trigger nerve pathways that create genuine back pain, typically resolving within days once acid reflux is properly managed
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