For glycemic control in type 2 diabetes, treatment is typically continued indefinitely as long as it remains effective and well-tolerated, with periodic assessment of the ongoing need for therapy
doi:10.1016/j.eclinm.2024.102475 Manne-Goehler J, Teufel F, Venter WDF
But those factors are not enough to offset what patients actually pay
After depolarization of presynaptic neurons, acetylcholine is released into the synaptic cleft and binds to postsynaptic receptors such as acetylcholine muscarinic receptors (mAchRs) or acetylcholine nicotinic receptors (nAchRs) (40)
doi: 10.1186/s10020-025-01318-y 201 WangXWanJWangCTongYChenYWangXet al
Doctors often recommend starting with a low dose and titrating up to find the amount that supports the persons goals while minimizing side effects, like gastrointestinal distress, fatigue, and an increased heart rate