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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood

Tissue remodeling, collagen synthesis, and vascular repair processes are well underway by this point, and the cumulative effects of consistent dosing become clearly apparent

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Several of these treatments are currently being investigated as tools to help rebuild damaged bone and cartilage in your joints