The FDA approved the Wegovy pill (oral semaglutide 25 mg, once daily) in late 2025, and it launched in the US in early January 2026
Nature Reviews Molecular Cell Biology
After the study, all models were histologically examined
Place your semaglutide in the fridge as soon as you arrive, before you unpack anything else
The medicinal-chemistry programme that produced cagrilintide, described by Kruse and colleagues in the Journal of Medicinal Chemistry in 2021, addressed this by re-engineering the amylin backbone with structural elements borrowed from calcitonin (a related, non-aggregating peptide) and attaching a fatty-acid side chain that enables reversible binding to serum albumin [1]
Peptides are short chains of amino acids, the building blocks of proteins, which play a crucial role in various bodily functions, including muscle growth and repair