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Clinical implications Going forward, clinicians may consider integrating GLP-1RAs into the treatment regimens for patients with [RA and obesity], not only to target obesity-related complications but also possibly to target the underlying inflammatory disease process, the authors concluded

While the clinical definition of hematochezia is the passage of bright red blood per rectum, ICD-10 groups this presentation under the category of gastrointestinal hemorrhage to distinguish it from hematemesis (K92.0) and unspecified GI hemorrhage (K92.2)

Always consult with your healthcare provider before beginning, modifying, or discontinuing any medication or treatment

This GAA-induced upregulation was significantly antagonized by co-treatment with the NRF2 inhibitor ML385 (Lu et al., 2025)

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