At the Hagedorn Research Institute, an academic center embedded within Novo Nordisk, a cell biologist named Ole Dragsbk Madsen had been giving rats tumors made from islet cells to study how the cells matured and turned on insulin gene expression
Some conditions warrant caution
Translation: the animals got leaner, stronger relative to their body weight, and ran better
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This resulted in reduced WAT mass, increased liver mass, impaired glucose tolerance and elevated circulating FAs, which is consistent with a primary defect in adipose lipid storage