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A subgroup analysis of the four trials investigating semaglutide as the intervention reported greater reduction in MACE than in the pooled analysis (HR (95% CI): 0.82(0.760.88))

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A meta-analysis of 5 RCTs 42,43,44,45,46 comprising 7,732 adults with T2DM did not observe any effect on cognition, as measured via mini-mental state examination (MMSE) or Montreal cognitive assessment (MoCA), of GLP-1RAs over several months compared with the baseline 38

With FDA-approved GLP-1s becoming more available and the compounded era coming to an end, theres never been a better time to ensure your weight management journey is built on a foundation of safety, efficacy, and transparency

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