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They work through a combination of many events, including weight loss and improving insulin sensitivity, says Cheng-Han Chen, MD, an interventional cardiologist and the medical director of the structural heart program at MemorialCare Saddleback Medical Center in Laguna Hills, California

Discontinuation rates due to adverse events remain low across studies (approximately 4-10%), indicating good overall tolerability

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It performs steadily in inhibiting melanin synthesis and is ideal for high-end users with established whitening habits