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Tirzepatide is the first in a class of drugs called dual GLP-1/GIP receptor agonists that activate the receptor for another gut hormone, glucose-dependent insulinotropic polypeptide (GIP), in addition to the GLP-1 receptor
Gallbladder problems: Gallstones or cholecystitis, especially with rapid weight loss
When to Contact Your Healthcare Provider About a Missed Dose Reach out to your healthcare provider if you've missed your semaglutide injection by more than three days, if you're unsure whether to take a late dose, or if you experience unusual symptoms after taking a delayed injection
Sore throat
Most incretin mimetics require subcutaneous injection, administered daily or weekly depending on the specific agent, though oral semaglutide (Rybelsus) is available
Previous analyses have suggested a larger benefit of SGLT-2 inhibitors, as compared with GLP-1RA, on cardiorenal events
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