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Ipamorelin is a synthetic pentapeptide classified as a selective growth hormone secretagogue that interacts with the ghrelin receptor (GHS R1a) in experimental systems

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A variant here, P478L, is associated with SPCD 55 , and in human OCT1, the equivalent residues are also implicated in the inward-outward conformational transition 29

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10.1242/jcs.202119 48 ScanlonJ