Given the individual benefits of semaglutide and tirzepatide, its natural to wonder if combining or alternating them could yield superior outcomes
That comparison can create unnecessary pressure
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Amgen started Phase III trials of MariTide, a once-monthly dual GLP-1 receptor agonist and GIP receptor antagonist, in March
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Its important to note, however, that the highest dose for semaglutide is now 2.2 mg (versus 1 mg used in the study), so more direct comparison is needed