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However, a systematic review in 2023 found only one phase 2 randomized controlled trial of exenatide versus placebo for IIH, which did demonstrate a significant reduction in ICP at all time points, as well as improved headache and visual acuity (7,8)

a GLP-1R expression detected by transgene expression in mice [65], density of GLP-1R-immunoreactive fibers in each brain region determined by rat immunocytochemistry [66], GLP-1R expression determined by ISH in non-human primates [67]

Heres what they found

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Juvenility of tobacco induced by cytokinin gene introduction decreases susceptibility to Tobacco necrosis virus and confers tolerance to oxidative stress