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For sustained energy, lifestyle foundations such as adequate sleep, nutrient intake, hydration, iron and B12 status, and physical conditioning should take priority, with L-carnitine considered only as an additional support

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These beneficial effects were underpinned by a comprehensive modulation of the transcriptome and proteome, revealing that semaglutide reduced systemic inflammation and mitigated fibrosis and lipid accumulation through direct effects on key cellular and molecular pathways, including enhanced branched-chain amino acid catabolism

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