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While GI side effects have been suggested to be involved in mediating the weight-loss effect of GLP-1RAs, analysis of large clinical trial data sets with liraglutide and semaglutide has shown that, while GI side effects may lead to more initial weight loss, they are not the mechanism of weight loss as many patients have weight loss and no side effects (182, 183)
Women taking semaglutide who are also on hormonal birth control or HRT face compounded risk factors
Vitamin B-12 is a crucial nutrient that plays a pivotal role in several vital bodily functions
Research confirms this is not theoretical
Researchers have not yet shown a clear biological mechanism that links GLP-1 agonists to depression or suicidal thoughts
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