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Phosphorylation of Y1135 and Y1131 destabilises the autoinhibitory conformation of the a-loop, whereas phosphorylation of Y1136 stabilises the catalytically optimised conformation of it (Favelyukis et al, 2001)

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Choi WM, Yip TC, Wong GL, Kim WR, Yee LJ, Brooks-Rooney C, Curteis T, Cant H, Chen CH, Chen CY, Huang YH, Jin YJ, Jun DW, Kim JW, Park NH, Peng CY, Shin HP, Shin JW, Yang YH, Lim YS