DOI: 10.1111/j.1537-2995.2010.03032.x 94
Ackeifi C, Swartz E, Kumar K et al
Beyond these examples, exercise also activates broader metabolic, oxidative stress, immune, and mechanotransduction programs, such as AMPK-PGC1 signaling [14,15,16], Nrf2-ARE antioxidant signaling [17], JAK-STAT immune signaling [18, 19], and mechanosensitive modules, including integrin-FAK-RhoA/ROCK signaling [20, 21], YAP/TAZ-Hippo signaling [22,23,24], and Piezo1-calcium signaling [25]
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77 They reported that 11 of 12 patients had reduced pain and improved function