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2) end-points, including HbA1c, body weight, SBP, lipids, number of patients achieving an HbA1c target of less than 7%, number of patients requiring rescue therapy due to hyperglycemia, incidence of hypoglycemic events

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This progressive destruction of thyroid tissue leads to reduced production of thyroid hormonesprimarily thyroxine (T4) and triiodothyronine (T3)which are essential for regulating metabolism, energy production, and numerous bodily functions

Because appetite is reduced, many people naturally eat less protein without realizing it