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Similarly, ERK (extracellular signal-regulated kinase) and its involvement in melanin synthesis via the ERK/CREB (cAMP response element binding protein) pathway demonstrate how kinases contribute not only to antioxidant defense but also to pigmentation regulation by upregulating MITF and TRP1 69,71
PMC 11751538
Devadas S, Hinshaw JA, Zaritskaya L, Williams MS
The effect of melanin in the skin is to protect your body from UV rays
Important: If you ever experience a severe allergic reactionsuch as swelling of the lips, face, or tongue, trouble breathing, or widespread hivescall 911 or go to your nearest emergency room immediately
The intervention consisted of 1,000 mg/day of long-chain omega-3 (189 mg EPA +120 mg DHA) for 8 weeks, compared with a placebo containing medium chain triglycerides
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