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Molecular mechanisms underlying the diabetogenic effects of AFs are not completely understood, however recent investigations reported that AFs metabolites, in particular AFB1, might influence the regulatory switches of specific signaling pathways, genes, transcription factors, and receptors such as IGF2 and IGF1 receptor IGF-IR (215)

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Murugesan A, Kari S, Shrestha A, Assoah B,Saravanan KM,Murugesan M, Thiyagarajan R, Candeias NR,Kandhavelu M