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Possible explanations include dehydration from gastrointestinal side effects like nausea, vomiting, or diarrhoea, and metabolic changes associated with the medication

doi: 10.4049/jimmunol.168.6.2603 126 TakahashiA.ShiotaS.MatsunariO.WatadaM.SuzukiR.NakachiS.et al