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In addition, forestomach tissues have the potential to convert HMB into Met, given the high enzymatic activities found in the rumen and omasum, which allows the conversion of D- and L-isomers of HMB into the L-Met precursor (Lobley et al., 2006b)
However, chronic exposure can promote stable increases in these metabolic phenotypes, as evidenced by our resistant organoid models (Extended Data Fig
E., Monk, K
2025;10(107):eadr4795
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Sterilise the vial stopper with 70% isopropyl alcohol before every needle insertion
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