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Canagliflozin significantly inhibits inflammatory factor expression, including cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase, exerting cardioprotective effects by regulating inflammation and ferroptosis through the AMP-activated protein kinase (AMPK) pathway (83)

These tissue regeneration research findings have implications for regenerative medicine approaches, understanding stem cell aging, and developing interventions that restore the body's natural repair capacity diminished by senescent cell accumulation

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These dermal effects are well documented and form the rationale for extending interest to the scalp, since the scalp is skin and the follicle is embedded in dermal tissue

Biochemistry of adipose tissue: an endocrine organ