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Medications : Diuretics (often used for hypertension or heart failure) and low-dose aspirin can impair uric acid excretion

Retrospective EHR-based studies can capture real-world associations, yet they are especially vulnerable to residual confounding, treatment-selection bias, differences in healthcare engagement, and unmeasured disease biology

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Researchers are responsible for establishing preparation, concentration, controls, and stability procedures appropriate to their validated methods

[3] ALCAR in the cytosol can also form a pool of acetyl-groups for CoA, should the cell need it

Separate direct evidence from theory