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Chronic stress and anxiety have been linked to lower glutathione levels, likely because the biochemical stress response generates free radicals that consume glutathione

IJPR 18, 13951402

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In addition, APV promoted clearance of fluorescent tracers in the para-arterial space in AQP4-deleted mice, suggesting that enhancement of glymphatic clearance by APV was not dependent on AQP4 and was more likely acts on blood vessels

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