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Source: Neurology Advisor
GLP-1, substance P, and BNP, commonly show a vasodilation effect, while NPY has a significant hypertensive effect
It impairs insulin sensitivity, sometimes by as much as 30% after just four nights of poor sleep
In the TRIUMPH-1 obesity trial, patients on the highest dose lost an average of about 28% of their body weight at 80 weeks, and a subgroup with higher starting weight lost up to about 30% at 104 weeks
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