10 Conclusion and perspectives DKD, a serious DM-related microvascular disorder, is pathologically defined by persistent hyperglycemia-triggered complex metabolic abnormalities, ultimately leading to glomerular filtration barrier destruction and tubulointerstitial injury (132, 224)
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179 HSP60 and HSP70 in mitochondrial control, stress adaptation, and immune modulation HSP60 plays dual role in tumor promotion and suppression HSP60 exhibits context-dependent roles in cancer, acting as either a tumor promoter or suppressor depending on the malignancy type
This association plays an important role in the progression of diabetes
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