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Este sndrome involucra una activacin excesiva del sistema inmunolgico con dao en otros rganos, lo que contribuye a su alta tasa de mortalidad
The GLP-1 analogs, semaglutide and liraglutide, delay the progression of atherosclerosis by regulating inflammatory pathways in low-density lipoprotein receptor-deficient (LDLr -/- ) and apolipoprotein E-deficient (ApoE -/- ) mice [16]
Moreover, a large-scale randomized controlled trial (RCTs) involving more than 17,000 individuals with obesity and cardiovascular disease demonstrated that semaglutide reduced the risk of cardiovascular death, myocardial infarction (MI), and stroke compared to the placebo 9
Ischemic stroke triggers a serious neuroinflammatory response [128, 129], which can harm neurons by releasing cytokines, chemokines, and oxidative stress-related factors
Tong-Qiao-Huo-Xue Decoction promotes synaptic remodeling via cAMP/ PKA/CREB pathway in vascular dementia rats
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