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Total combined all-cause mortality and cardiac morbidity events were 222/571 (39%) for patients on amlodipine besylate and 246/583 (42%) for patients on placebo

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Blood 129:15481556 Macharia AW, Mochamah G, Uyoga S et al (2018) The clinical epidemiology of SCD in Africa

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Method of Administration: Intravenous or intramuscular Treatment Protocol: For severe cases, 600 to 1200mg is administered intravenously or intramuscularly once daily through an IV drip or infusion over 10 treatment sessions