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It may mitigate oxidative stress, preserving vascular integrity and function

PubMed Chang CH, Tsai WC, Lin MS, et al

273 In addition, in a rat model of inflammatory OA induced by monoiodoacetic acid (MIA), researchers have shown that the activation of GLP-1R triggers the PKA/CREB signaling pathway, leading to a reduction in cartilage inflammation

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Link This suggests oral B12 with SNAC may offer a superior alternative to standard oral formulations, especially for patients with malabsorption or injection intolerance