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In: Honig A, Van Praag HM (eds) Depression: Neurobiological, Psychological and Therapeutic Advances John Wiley & Sons: New York 1997

The synergistic potential lies in addressing different aspects of weight regulation

In adults with obesity who achieved weight loss on a low-calorie diet, adding liraglutide, a GLP-1 receptor agonist, plus regular moderate-to-vigorous exercise for one year further lowered metabolic syndrome severity and abdominal fat

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GLP-1 receptor agonists, also known as GLP-1 analogues, reduce blood sugar levels and appetite

Patients typically notice gradual, natural-looking improvements over several months without the need for surgical skin tightening