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Of particular interest are the paracrine effects of adipokines and gastrointestinal substrates regulated by DPP-4, such as leptin, adiponectin, pancreatic peptide YY (PYY), and glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2), which may mediate the crosstalk between bone remodeling and energy metabolism [2, 24]

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The synthesis of the different thyroid hormones occurs in 5 steps as in Fig

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GHK-Cu stimulates both collagen and elastin production in human dermal fibroblasts, at concentrations as low as 0.01 nM [3]

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