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Description

5.2 Mitochondrial dysfunction Mitochondrial dysfunction plays a pivotal role in the pathogenesis of HTN-related OS, acting as both a major source and a vulnerable target of ROS in the cardiovascular system

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Activated IGF-1R transduced the signal 49,50 to AKT as increased levels of pAKT were observed in GNE knockdown and mutant cells (Fig

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mGSH=glutathionie (mitochondrial)

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