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For some people, Mounjaro may be associated with temporary feelings of anxiety or low mood

Findings: RCTSemaglutide vs Placebo for Alcohol Use Disorder in Adults, JAMA Psychiatry (2025) [PubMed abstract] Design: Randomized, placebo-controlled trial (N=48 | length = 9 weeks) in non-treatment-seeking adults with alcohol use disorder Treatment: Semaglutide (0.25 mg/week for 4 weeks, 0.5 mg/week for 4 weeks, and 1.0 mg for 1 week) vs Placebo Primary outcome: Objective alcohol self-administration (at baseline and between Weeks 8 and 9) measured as follows: a standardized procedure was used to estimate voluntary alcohol consumption and ability to delay drinking

This keeps patients safe and your processes consistent

53(3): 338-344 Health Canada

The connection is direct, well-documented, and mechanistically clear

Organ-growth changes are believed to be largely irreversible, which is the strongest argument behind the 4-6 week cycle ceiling