Yes, some individuals experience mild abdominal cramping, bloating, or discomfort when taking vitamin B12 supplements, particularly on an empty stomach or with higher-dose formulations
They've become popular among teens on TikTok, especially boys, over unproven claims that certain peptides can help with building muscle mass and enhancing your body, with some online using phrases like "biohacking" and "looksmaxxing" to describe the trend
Vidal-Alaball J, Butler CC, Potter CC: Comparing costs of intramuscular and oral vitamin B12 administration in primary care: a cost-minimization analysis
Int J Drug Deliv 4 Pawar PP, Ghorpade HS, Kokane BA (2018) Sublingual route for systemic drug delivery
In particular, B12 and Folate are important for the health of the brain, nerves, blood cells, intestines, and heart