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a more favorable option for some patients Side Effects: Black Box Warning: RISK OF THYROID C-CELL TUMORS Reference: rxlist.com (Tanzeum) Dulaglutide Drug Name: Trulicity (FDA Approved 9/18/14) GLP-1 receptor agonist, hypoglycemic Pharmacokinetics: Long acting (half life: 5 days) subcutaneous pen injections weekly dosing (vs daily dosing for some other GLP-1 agonists such as exenatide, liraglutide & lixisenatide) a more favorable dosing option for some patients Side Effects: Black Box Warning: RISK OF THYROID C-CELL TUMORS References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)

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The remaining cases received saxagliptin (0.06%) and exenatide extended release (ER) (33%)

A few large, insurer-owned PBMs control much of the pharmacy supply chain and rebate dynamics

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This steady and gradual decline in body weight is a positive indicator that the medication is working effectively